Endocrine Abstracts

Background: Fine needle aspiration biopsy (FNAB) has proven to be the most valuable diagnostic procedure for preoperative discrimination of benign and malignant nodules. Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) has standardized reporting and cytomorphological criteria in aspiration smears. In this study, we aimed to determine malignancy rates in nodules with different cytology results and diagnostic value of TBSRTC for variants of papillary thyroid carcinom...

Introduction: In this study, we aimed to evaluate impact of multifocality, tumor number and total tumor diameter on clinicopathological features of PTC.Methods: Medical records of 912 patients who underwent thyroidectomy and diagnosed with PTC were reviewed retrospectively. Patients were grouped into 4 according to number of tumoral foci; N1 (1 focus), N2 (2 foci), N3 (3 foci) and N4 (≥ 4 foci). The diameter of the largest tumor was considered as t...

Introduction: The increased rate of thyroid malignancy as well as incidental and subcentimeter thyroid nodules have been attributed to increasing use of high-resolution US which can detect the non-palpabl or subcentimeter (maximum diameter ≤1 cm) thyroid nodules. We aimed to evaluate the sonographic features of the tyroid nodules between ≤1 cm and > 1 cm according the histopathology results and to determine the ultrasonographical predictive factors for malignan...

Introduction: In this study, we aimed to evaluate the usefulness of ratio of primary tumor diameter to total tumor diameter as a new parameter for the differentiation of agressive and favorable papillary thyroid microcarcinomas (PTMC).Methods: The diameter of the largest tumor focus was taken as the primary tumour diameter (PTD). For multifocal tumors, total tumor diameter (TTD) was calculated as the sum of the maximal diameter of each lesion. A ratio wa...

Introduction: Primary hyperparathyroidism (PHP) is a highly prevalent disease, which is treated most effectively by surgery. Postoperative hypocalcaemia, a morbidity of surgical treatment of parathyroidism, can prolong the hospital stay. The aim of this study was to identify the factors predictive of hypocalcaemia and hungry bone syndrome (HBS) in patients who undergo parathyroidectomy due to PHP.Materials and methods: Preoperatively and on days 1 and 4,...

Introduction: Ocular changes are common in various endocrine disorders. However, there are only few studies reporting ocular changes in patients with primary hyperparathyroidism (PHPT). Here, we examined central corneal thickness (CCT) and retinal thickness (RT), intraocular pressure (IOP) and their relationships with serum intact parathyroid hormone (iPTH), calcium (Ca), and phosphorus levels in PHPT patients.Methods: Thirty-seven patients with PHPT wer...

Introduction: Primary hyperparathyroidism (pHPT) is a common endocrine disease mainly caused by single or multiple hyperfunctioning parathyroid lesions. In 2–7% of cases, surgery is not curative at first operation and reoperation is required. Ultrasonography and sestamibi scan are the most widely used methods for identification of the culprit parathyroid gland with the disadvantage of high false positives caused by other cervical pathologies. Herein we aimed to search the...

Introduction: Reoperative surgery for thyroid disease is rare. It is sometimes indicated for nodular recurrence after partial surgery for initially benign thyroid disease or for a completion total thyroidectomy when a final diagnosis of thyroid cancer is confirmed on a permanent section of a partially removed thyroid gland. We aimed to investigate the demographic features and reoperation indications in patients with reoperative thyroidectomy.Methods: Thi...

Introduction: Radioactive iodine (RAI) therapy is widely used in the treatment of hyperthyroidism especially in patients with Graves’ disease (GD), toxic multinodular goitre (TMNG), and toxic adenoma. RAI may lead to worsening of the autoimmunity with the elevation of TSH-receptor antibody (TRAB). In this study, we aimed to compare the effects of surgery or RAI treatment on TRAB.Methods: Hyperthyroid patients were divided into three groups; patients...

Introduction: We report stage IV B cell lymphoma in a patient presenting with adrenal failure and an intraabdominal mass which imaging techniques were suggestive for paraganglioma.Case report: A 71-years-old woman admitted to our emergency clinic with severe fatigue and stupor. She was diagnosed to have primary adrenal failure since serum ACTH was 229 pg/ml and cortisol response to 250 μg co-syntropin was 6.17 μg/dl. In abdominal MRI, bilateral...